Search results for "nuchal translucency"

Automatic detection and measurement of nuchal translucency.

2017

In this paper we propose a new methodology to support the physician both to identify automatically the nuchal region and to obtain a correct thickness measurement of the nuchal translucency. The thickness of the nuchal translucency is one of the main markers for screening of chromosomal defects such as trisomy 13, 18 and 21. Its measurement is performed during ultrasound scanning in the first trimester of pregnancy. The proposed methodology is mainly based on wavelet and multi resolution analysis. The performance of our method was analysed on 382 random frames, representing mid-sagittal sections, uniformly extracted from real clinical ultrasound videos of 12 patients. According to the groun…

First-trimester screening for trisomy-21 using a simplified method to assess the presence or absence of the fetal nasal bone.

2005

Objective To determine the benefit of including nasal bone assessment in addition to standard first-trimester markers (nuchal translucency, free beta human chorionic gonadotropin and pregnancy-associated plasma protein A) as a screening test for Down syndrome, using a strict criterion for classification of nasal bone absence. Study design Nasal bone assessment was conducted in 2411 patients with crown-rump length between 45 and 84 mm, including 15 patients with Down syndrome. A patient was considered to have an absent nasal bone only if there was no evidence of present nasal bone. Unlike other studies, nasal bone was classified as present when there was evidence of a thin echogenic line und…

Morphological Analysis Combined with a Machine Learning Approach to Detect Utrasound Median Sagittal Sections for the Nuchal Translucency Measurement

2017

The screening of chromosomal defects, as trisomy 13, 18 and 21, can be obtained by the measurement of the nuchal translucency thickness scanning during the end of the first trimester of pregnancy. This contribution proposes an automatic methodology to detect mid-sagittal sections to identify the correct measurement of nuchal translucency. Wavelet analysis and neural network classifiers are the main strategies of the proposed methodology to detect the frontal components of the skull and the choroid plexus with the support of radial symmetry analysis. Real clinical ultrasound images were adopted to measure the performance and the robustness of the methodology, thus it can be highlighted an er…

A non-supervised approach to locate and to measure the nuchal translucency by means of wavelet analysis and neural networks

2017

Ultrasound imaging is a well known noninvasive way to evaluate various diseases during the prenatal age. In particular, the thickness measure of the nuchal transucency is strictly correlated with pathologies like trisomy 13, 18 and 21. For a correct investigation, the methodology needs mid-sagittal sections and the proposed approach is based on wavelet analysis and neural network classifiers to locate components useful to identify mid-sagittal planes. To evaluate the performance and the robustness of the methodology, real clinical ultrasound images were considered, obtaining an average error of at most 0.3 millimeters in 97.4% of the cases.

Goal-directed junior ultrasound training in quantitative measurement of crown-rump length and fetal nuchal translucency: evaluation of a specific tra…

2015

Doubtful association between TAR syndrome and increased nuchal translucency in the first trimester of pregnancy

2006

Major Congenital Anomalies in Babies Born With Down Syndrome

2014

Previous studies have shown that over 40% of babies with Down syndrome have a major cardiac anomaly and are more likely to have other major congenital anomalies. Since 2000, many countries in Europe have introduced national antenatal screening programs for Down syndrome. This study aimed to determine if the introduction of these screening programs and the subsequent termination of prenatally detected pregnancies were associated with any decline in the prevalence of additional anomalies in babies born with Down syndrome. The study sample consisted of 7,044 live births and fetal deaths with Down syndrome registered in 28 European population-based congenital anomaly registries covering seven m…

Doubtful association between progesterone therapy and fetal nuchal translucency

2015

Wavelet analysis and neural network classifiers to detect mid-sagittal sections for nuchal translucency measurement

2016

We propose a methodology to support the physician in the automatic identification of mid-sagittal sections of the fetus in ultrasound videos acquired during the first trimester of pregnancy. A good mid-sagittal section is a key requirement to make the correct measurement of nuchal translucency which is one of the main marker for screening of chromosomal defects such as trisomy 13, 18 and 21. NT measurement is beyond the scope of this article. The proposed methodology is mainly based on wavelet analysis and neural network classifiers to detect the jawbone and on radial symmetry analysis to detect the choroid plexus. Those steps allow to identify the frames which represent correct mid-sagitta…

Association of first trimester fetal heart rate and nuchal translucency with preterm birth.

2021

To evaluate whether first trimester fetal heart rate (FHR) and nuchal translucency (NT) associate with preterm birth (PTB).This was a comparative case-control study of 518 normal pregnancies with no history of PTB, of which 272 delivered at term (TB) and 246 progressed to spontaneous PTB prior to 37, 34, 32, and 28 weeks. Fetal heart rate (FHR) and NT values at the first-trimester scan were compared by means of univariable (Mann-Whitney) and multivariable logistic regression analysis considering hourglass membranes (HM) as the most severe PTB subgroup. Finally, severity trends for both parameters were investigated using correlations with gestational age (GA) at delivery and Kruskal-Walls te…